Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Arajet

The cheapest airline(s) flying from Santo Domingo to Medellin is Arajet.

  • Arajet Arajet
  • Avianca Avianca
  • Copa Airlines Copa Airlines
Cheapest Month December

Travel Period: October 2024 - September 2025

The cheapest month(s) to fly from Santo Domingo to Medellin is December.

  • Oct 2024
  • Nov 2024
  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
Cheapest Day of the Week Friday

The cheapest day(s) of the week to fly from Santo Domingo to Medellin is Friday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Sep, 2024

  • Time Earliest
    • Earliest
    • Latest
  • Depart Earliest
    • Earliest
    • Latest
  • Arrive
    • Earliest
    • Latest
  • Duration
    • Shortest
    • Longest
  • Stopover
    All
    • Airline Filter by Airline
      View All Airline
      • Availability
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 21:28 SDQ
        22:58 MDE
        2Hrs, 30m Direct
      • SDQSanto Domingo Las Americas Airport 21:28 - MDE 22:58 2h 30m Direct
      • SDQSanto Domingo Las Americas Airport 21:28
      • MDEMedellin Jose Maria Cordova Intl Airport 22:58
      • 2h 30m
      • Direct
      • Wingo (P5 7423)Boeing 737 800
      • Wingo (P5 7423)
        • -
        • -
        • W
        • -
        • -
        • S
        • -
      • Boeing 737 800
      • 06:00 SDQ
        07:25 MDE
        2Hrs, 25m Direct
      • SDQSanto Domingo Las Americas Airport 06:00 - MDE 07:25 2h 25m Direct
      • SDQSanto Domingo Las Americas Airport 06:00
      • MDEMedellin Jose Maria Cordova Intl Airport 07:25
      • 2h 25m
      • Direct
      • Arajet (DM 1731)Boeing 737 Max 8 Passenger
      • Arajet (DM 1731)
        • M
        • -
        • -
        • -
        • F
        • -
        • -
      • Boeing 737 Max 8 Passenger
      • 07:30 SDQ
        10:35 MDE
        4Hrs, 05m Direct
      • SDQSanto Domingo Las Americas Airport 07:30 - MDE 10:35 4h 05m Direct
      • SDQSanto Domingo Las Americas Airport 07:30
      • MDEMedellin Jose Maria Cordova Intl Airport 10:35
      • 4h 05m
      • Direct
      • Arajet (DM 1003)Boeing 737 Max 8 Passenger
      • Arajet (DM 1003)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • Boeing 737 Max 8 Passenger
      • 11:24 SDQ
        12:53 MDE
        2Hrs, 29m Direct
      • SDQSanto Domingo Las Americas Airport 11:24 - MDE 12:53 2h 29m Direct
      • SDQSanto Domingo Las Americas Airport 11:24
      • MDEMedellin Jose Maria Cordova Intl Airport 12:53
      • 2h 29m
      • Direct
      • Wingo (P5 7421)Boeing 737 800
      • Wingo (P5 7421)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • Boeing 737 800
      • 13:30 SDQ
        16:35 MDE
        4Hrs, 05m Direct
      • SDQSanto Domingo Las Americas Airport 13:30 - MDE 16:35 4h 05m Direct
      • SDQSanto Domingo Las Americas Airport 13:30
      • MDEMedellin Jose Maria Cordova Intl Airport 16:35
      • 4h 05m
      • Direct
      • Arajet (DM 1001)Boeing 737 Max 8 Passenger
      • Arajet (DM 1001)
        • -
        • -
        • W
        • -
        • -
        • -
        • -
      • Boeing 737 Max 8 Passenger
      • 18:15 SDQ
        19:40 MDE
        2Hrs, 25m Direct
      • SDQSanto Domingo Las Americas Airport 18:15 - MDE 19:40 2h 25m Direct
      • SDQSanto Domingo Las Americas Airport 18:15
      • MDEMedellin Jose Maria Cordova Intl Airport 19:40
      • 2h 25m
      • Direct
      • Arajet (DM 1737)Boeing 737 Max 8 Passenger
      • Arajet (DM 1737)
        • -
        • T
        • -
        • T
        • -
        • -
        • S
      • Boeing 737 Max 8 Passenger
      • 06:32 SDQ
        10:32 MDE
        5Hrs, 00m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 06:32 - MDE 10:32 5h 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 06:32
        PTYPanama City Tocumen International Airport 09:08
      • PTYPanama City Tocumen International Airport 08:05
        MDEMedellin Jose Maria Cordova Intl Airport 10:32
      • 5h (1h 03m)
      • 1 Stop PTY · Panama City 1h 03m
      • Copa Airlines (CM 108)Boeing 737 700
        Copa Airlines (CM 855)Boeing 737 800
      • Copa Airlines (CM 108)
        • -
        • -
        • -
        • T
        • F
        • S
        • -
      • 06:32 SDQ
        10:55 MDE
        5Hrs, 23m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 06:32 - MDE 10:55 5h 23m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 06:32
        PTYPanama City Tocumen International Airport 09:31
      • PTYPanama City Tocumen International Airport 08:05
        MDEMedellin Jose Maria Cordova Intl Airport 10:55
      • 5h 23m (1h 26m)
      • 1 Stop PTY · Panama City 1h 26m
      • Copa Airlines (CM 108)Boeing 737 700
        Copa Airlines (CM 397)Boeing 737 800
      • Copa Airlines (CM 108)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 08:55 SDQ
        14:12 MDE
        6Hrs, 17m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 08:55 - MDE 14:12 6h 17m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 08:55
        PTYPanama City Tocumen International Airport 12:48
      • PTYPanama City Tocumen International Airport 10:28
        MDEMedellin Jose Maria Cordova Intl Airport 14:12
      • 6h 17m (2h 20m)
      • 1 Stop PTY · Panama City 2h 20m
      • Copa Airlines (CM 267)Boeing 737 800
        Copa Airlines (CM 502)Boeing 737 800
      • Copa Airlines (CM 267)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 09:58 SDQ
        16:55 MDE
        7Hrs, 57m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 09:58 - MDE 16:55 7h 57m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 09:58
        BOGBogota Airport 15:56
      • BOGBogota Airport 11:33
        MDEMedellin Jose Maria Cordova Intl Airport 16:55
      • 7h 57m (4h 23m)
      • 1 Stop BOG · Bogota 4h 23m
      • Wingo (P5 7083)Boeing 737 800
        Wingo (P5 7274)Boeing 737 800
      • Wingo (P5 7083)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 11:45 SDQ
        16:32 MDE
        5Hrs, 47m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 11:45 - MDE 16:32 5h 47m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 11:45
        BOGBogota Airport 15:30
      • BOGBogota Airport 13:20
        MDEMedellin Jose Maria Cordova Intl Airport 16:32
      • 5h 47m (2h 10m)
      • 1 Stop BOG · Bogota 2h 10m
      • Avianca (AV 209)Airbus A320 Neo
        Avianca (AV 9310)Airbus
      • Avianca (AV 209)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 11:45 SDQ
        16:51 MDE
        6Hrs, 06m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 11:45 - MDE 16:51 6h 06m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 11:45
        BOGBogota Airport 15:50
      • BOGBogota Airport 13:20
        MDEMedellin Jose Maria Cordova Intl Airport 16:51
      • 6h 06m (2h 30m)
      • 1 Stop BOG · Bogota 2h 30m
      • Avianca (AV 209)Airbus A320 Neo
        Avianca (AV 9324)Airbus
      • Avianca (AV 209)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 11:57 SDQ
        17:01 MDE
        6Hrs, 04m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 11:57 - MDE 17:01 6h 04m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 11:57
        PTYPanama City Tocumen International Airport 15:37
      • PTYPanama City Tocumen International Airport 13:30
        MDEMedellin Jose Maria Cordova Intl Airport 17:01
      • 6h 04m (2h 07m)
      • 1 Stop PTY · Panama City 2h 07m
      • Copa Airlines (CM 129)Boeing 737 Max 9 Passenger
        Copa Airlines (CM 156)Boeing 737 800
      • Copa Airlines (CM 129)
        • M
        • T
        • W
        • -
        • F
        • S
        • S
      • 11:57 SDQ
        17:01 MDE
        6Hrs, 04m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 11:57 - MDE 17:01 6h 04m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 11:57
        PTYPanama City Tocumen International Airport 15:37
      • PTYPanama City Tocumen International Airport 13:30
        MDEMedellin Jose Maria Cordova Intl Airport 17:01
      • 6h 04m (2h 07m)
      • 1 Stop PTY · Panama City 2h 07m
      • Copa Airlines (CM 129)Boeing 737 800
        Copa Airlines (CM 156)Boeing 737 800
      • Copa Airlines (CM 129)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 12:00 SDQ
        17:01 MDE
        6Hrs, 01m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 12:00 - MDE 17:01 6h 01m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 12:00
        PTYPanama City Tocumen International Airport 15:37
      • PTYPanama City Tocumen International Airport 13:40
        MDEMedellin Jose Maria Cordova Intl Airport 17:01
      • 6h 01m (1h 57m)
      • 1 Stop PTY · Panama City 1h 57m
      • Copa Airlines (CM 870)Boeing 737 800
        Copa Airlines (CM 156)Boeing 737 800
      • Copa Airlines (CM 870)
        • M
        • -
        • -
        • T
        • -
        • -
        • S
      • 14:45 SDQ
        20:09 MDE
        6Hrs, 24m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 14:45 - MDE 20:09 6h 24m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 14:45
        PTYPanama City Tocumen International Airport 18:45
      • PTYPanama City Tocumen International Airport 16:18
        MDEMedellin Jose Maria Cordova Intl Airport 20:09
      • 6h 24m (2h 27m)
      • 1 Stop PTY · Panama City 2h 27m
      • Copa Airlines (CM 299)Boeing 737 700
        Copa Airlines (CM 208)Boeing 737 800
      • Copa Airlines (CM 299)
        • M
        • T
        • W
        • -
        • F
        • -
        • S
      • 14:45 SDQ
        20:19 MDE
        6Hrs, 34m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 14:45 - MDE 20:19 6h 34m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 14:45
        PTYPanama City Tocumen International Airport 18:55
      • PTYPanama City Tocumen International Airport 16:18
        MDEMedellin Jose Maria Cordova Intl Airport 20:19
      • 6h 34m (2h 37m)
      • 1 Stop PTY · Panama City 2h 37m
      • Copa Airlines (CM 299)Boeing 737 700
        Copa Airlines (CM 163)Boeing 737 800
      • Copa Airlines (CM 299)
        • M
        • -
        • W
        • -
        • F
        • -
        • -
      • 14:45 SDQ
        20:09 MDE
        6Hrs, 24m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 14:45 - MDE 20:09 6h 24m 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 14:45
        PTYPanama City Tocumen International Airport 18:45
      • PTYPanama City Tocumen International Airport 16:18
        MDEMedellin Jose Maria Cordova Intl Airport 20:09
      • 6h 24m (2h 27m)
      • 1 Stop PTY · Panama City 2h 27m
      • Copa Airlines (CM 299)Boeing 737 800
        Copa Airlines (CM 208)Boeing 737 800
      • Copa Airlines (CM 299)
        • -
        • -
        • -
        • T
        • -
        • S
        • -
      • 17:50 SDQ
        22:50 MDE
        6Hrs, 00m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 17:50 - MDE 22:50 6h 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 17:50
        PTYPanama City Tocumen International Airport 21:26
      • PTYPanama City Tocumen International Airport 19:23
        MDEMedellin Jose Maria Cordova Intl Airport 22:50
      • 6h (2h 03m)
      • 1 Stop PTY · Panama City 2h 03m
      • Copa Airlines (CM 464)Boeing 737 800
        Copa Airlines (CM 155)Boeing 737 700
      • Copa Airlines (CM 464)
        • -
        • -
        • -
        • -
        • F
        • -
        • S
      • 17:50 SDQ
        22:50 MDE
        6Hrs, 00m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 17:50 - MDE 22:50 6h 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 17:50
        PTYPanama City Tocumen International Airport 21:26
      • PTYPanama City Tocumen International Airport 19:23
        MDEMedellin Jose Maria Cordova Intl Airport 22:50
      • 6h (2h 03m)
      • 1 Stop PTY · Panama City 2h 03m
      • Copa Airlines (CM 464)Boeing 737 800
        Copa Airlines (CM 155)Boeing 737 800
      • Copa Airlines (CM 464)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 17:50 SDQ
        22:50 MDE
        6Hrs, 00m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 17:50 - MDE 22:50 6h 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 17:50
        PTYPanama City Tocumen International Airport 21:26
      • PTYPanama City Tocumen International Airport 19:23
        MDEMedellin Jose Maria Cordova Intl Airport 22:50
      • 6h (2h 03m)
      • 1 Stop PTY · Panama City 2h 03m
      • Copa Airlines (CM 464)Boeing 737 700
        Copa Airlines (CM 155)Boeing 737 800
      • Copa Airlines (CM 464)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 17:50 SDQ
        22:50 MDE
        6Hrs, 00m 1 Stop (PTY)
      • SDQSanto Domingo Las Americas Airport 17:50 - MDE 22:50 6h 1 Stop (PTY) Panama City
      • SDQSanto Domingo Las Americas Airport 17:50
        PTYPanama City Tocumen International Airport 21:26
      • PTYPanama City Tocumen International Airport 19:23
        MDEMedellin Jose Maria Cordova Intl Airport 22:50
      • 6h (2h 03m)
      • 1 Stop PTY · Panama City 2h 03m
      • Copa Airlines (CM 464)Boeing 737 700
        Copa Airlines (CM 155)Boeing 737 700
      • Copa Airlines (CM 464)
        • M
        • -
        • W
        • -
        • -
        • S
        • -
      • 18:20 SDQ
        23:01 MDE
        5Hrs, 41m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 18:20 - MDE 23:01 5h 41m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 18:20
        BOGBogota Airport 21:59
      • BOGBogota Airport 19:55
        MDEMedellin Jose Maria Cordova Intl Airport 23:01
      • 5h 41m (2h 04m)
      • 1 Stop BOG · Bogota 2h 04m
      • Avianca (AV 251)Airbus
        Avianca (AV 8449)Airbus
      • Avianca (AV 251)
        • -
        • -
        • -
        • -
        • -
        • S
        • S
      • 18:20 SDQ
        23:08 MDE
        5Hrs, 48m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 18:20 - MDE 23:08 5h 48m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 18:20
        BOGBogota Airport 22:11
      • BOGBogota Airport 19:55
        MDEMedellin Jose Maria Cordova Intl Airport 23:08
      • 5h 48m (2h 16m)
      • 1 Stop BOG · Bogota 2h 16m
      • Avianca (AV 251)Airbus
        Avianca (AV 9314)Airbus
      • Avianca (AV 251)
        • -
        • -
        • -
        • -
        • -
        • S
        • S
      • 18:20 SDQ
        23:08 MDE
        5Hrs, 48m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 18:20 - MDE 23:08 5h 48m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 18:20
        BOGBogota Airport 22:11
      • BOGBogota Airport 19:55
        MDEMedellin Jose Maria Cordova Intl Airport 23:08
      • 5h 48m (2h 16m)
      • 1 Stop BOG · Bogota 2h 16m
      • Avianca (AV 251)Airbus A320 Neo
        Avianca (AV 9314)Airbus
      • Avianca (AV 251)
        • M
        • T
        • -
        • T
        • F
        • -
        • -
      • 18:20 SDQ
        23:24 MDE
        6Hrs, 04m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 18:20 - MDE 23:24 6h 04m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 18:20
        BOGBogota Airport 22:25
      • BOGBogota Airport 19:55
        MDEMedellin Jose Maria Cordova Intl Airport 23:24
      • 6h 04m (2h 30m)
      • 1 Stop BOG · Bogota 2h 30m
      • Avianca (AV 251)Airbus A320 Neo
        Avianca (AV 9244)Airbus A320 Neo
      • Avianca (AV 251)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 18:20 SDQ
        23:01 MDE
        5Hrs, 41m 1 Stop (BOG)
      • SDQSanto Domingo Las Americas Airport 18:20 - MDE 23:01 5h 41m 1 Stop (BOG) Bogota
      • SDQSanto Domingo Las Americas Airport 18:20
        BOGBogota Airport 21:59
      • BOGBogota Airport 19:55
        MDEMedellin Jose Maria Cordova Intl Airport 23:01
      • 5h 41m (2h 04m)
      • 1 Stop BOG · Bogota 2h 04m
      • Avianca (AV 251)Airbus A320 Neo
        Avianca (AV 8449)Airbus
      • Avianca (AV 251)
        • -
        • -
        • -
        • T
        • F
        • -
        • -
      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      What’s the fastest flight time from Santo Domingo to Medellin?

      The fastest flight time for direct flights from Santo Domingo to Medellin is 2 hours 25 minutes. Check latest flight schedules & prices on Wego.

      What’s the most popular airline flying from Santo Domingo to Medellin?

      The most popular airline flying from Santo Domingo to Medellin is Arajet. Find the latest flight deals on Wego.

      How far is Medellin from Santo Domingo?

      The flight distance between Santo Domingo and Medellin is 1493km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 06:00. The last flight of the day departs at 21:28. See the full list of flight times on Wego.

      How many airlines offer direct flights from Santo Domingo to Medellin?

      There are 2 airlines that offer direct flights from Santo Domingo to Medellin. Find out the list of airlines on Wego.

      Popular Airlines flying from Santo Domingo to Medellin

      Arajet ‏()
      Wingo ‏()

      Popular Destinations from Medellin

      Popular Destinations from Santo Domingo

      Popular Hotels in Medellin

      Hotels In Popular Destinations