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Fare Guide

Estimated lowest fares found within 7 days

The cheapest airline(s) flying from Santo Domingo to Santiago is Avianca.

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Santo Domingo to Santiago is March.

Dec 2024
Jan 2025
Feb 2025
Mar 2025
Apr 2025
May 2025
Jun 2025
Jul 2025
Aug 2025
Sep 2025
Oct 2025
Nov 2025

The cheapest day(s) of the week to fly from Santo Domingo to Santiago is Tuesday.

Sun Sunday
Mon Monday
Tue Tuesday
Wed Wednesday
Thu Thursday
Fri Friday
Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

Time Earliest
- Earliest
- Latest
Depart Earliest
- Earliest
- Latest
Arrive
- Earliest
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Duration
- Shortest
- Longest
Stopover
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06:16 SDQ

20:12 SCL

12Hrs, 56m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 06:16 - SCL 20:12 12h 56m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 06:16

PTYPanama City Tocumen International Airport 11:47
PTYPanama City Tocumen International Airport 08:00

SCLSantiago Arturo Merino Benitez Airport 20:12
12h 56m (3h 47m)
1 Stop PTY · Panama City 3h 47m
Copa Airlines (CM 108)Boeing 737 800

Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
Copa Airlines (CM 108)
- -
- -
- -
- -
- -
- S
- -

06:16 SDQ

20:12 SCL

12Hrs, 56m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 06:16 - SCL 20:12 12h 56m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 06:16

PTYPanama City Tocumen International Airport 11:47
PTYPanama City Tocumen International Airport 08:00

SCLSantiago Arturo Merino Benitez Airport 20:12
12h 56m (3h 47m)
1 Stop PTY · Panama City 3h 47m
Copa Airlines (CM 108)Boeing 737 700

Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
Copa Airlines (CM 108)
- -
- T
- W
- T
- F
- -
- -

06:23 SDQ

20:20 SCL

12Hrs, 57m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 06:23 - SCL 20:20 12h 57m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 06:23

PTYPanama City Tocumen International Airport 11:47
PTYPanama City Tocumen International Airport 08:00

SCLSantiago Arturo Merino Benitez Airport 20:20
12h 57m (3h 47m)
1 Stop PTY · Panama City 3h 47m
Copa Airlines (CM 108)Boeing 737 700

Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
Copa Airlines (CM 108)
- -
- -
- -
- -
- -
- -
- S

08:53 SDQ

20:12 SCL

10Hrs, 19m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 08:53 - SCL 20:12 10h 19m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 08:53

PTYPanama City Tocumen International Airport 11:47
PTYPanama City Tocumen International Airport 10:30

SCLSantiago Arturo Merino Benitez Airport 20:12
10h 19m (1h 17m)
1 Stop PTY · Panama City 1h 17m
Copa Airlines (CM 267)Boeing 737 800

Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
Copa Airlines (CM 267)
- M
- T
- W
- T
- F
- S
- -

08:53 SDQ

20:20 SCL

10Hrs, 27m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 08:53 - SCL 20:20 10h 27m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 08:53

PTYPanama City Tocumen International Airport 11:47
PTYPanama City Tocumen International Airport 10:30

SCLSantiago Arturo Merino Benitez Airport 20:20
10h 27m (1h 17m)
1 Stop PTY · Panama City 1h 17m
Copa Airlines (CM 267)Boeing 737 800

Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
Copa Airlines (CM 267)
- -
- -
- -
- -
- -
- -
- S

08:53 SDQ

23:47 SCL

13Hrs, 54m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 08:53 - SCL 23:47 13h 54m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 08:53

PTYPanama City Tocumen International Airport 15:14
PTYPanama City Tocumen International Airport 10:30

SCLSantiago Arturo Merino Benitez Airport 23:47
13h 54m (4h 44m)
1 Stop PTY · Panama City 4h 44m
Copa Airlines (CM 267)Boeing 737 800

Copa Airlines (CM 497)Boeing 737 800
Copa Airlines (CM 267)
- M
- T
- -
- T
- F
- -
- -

08:53 SDQ

00:05 SCL

14Hrs, 12m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 08:53 - SCL 00:05 14h 12m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 08:53

PTYPanama City Tocumen International Airport 15:32
PTYPanama City Tocumen International Airport 10:30

SCLSantiago Arturo Merino Benitez Airport 00:05
14h 12m (5h 02m)
1 Stop PTY · Panama City 5h 02m
Copa Airlines (CM 267)Boeing 737 800

Copa Airlines (CM 171)Boeing 737 800
Copa Airlines (CM 267)
- -
- -
- W
- -
- -
- S
- S

11:50 SDQ

23:40 SCL

10Hrs, 50m 1 Stop (BOG)
SDQSanto Domingo Las Americas Airport 11:50 - SCL 23:40 10h 50m 1 Stop (BOG) Bogota
SDQSanto Domingo Las Americas Airport 11:50

BOGBogota Airport 15:30
BOGBogota Airport 13:25

SCLSantiago Arturo Merino Benitez Airport 23:40
10h 50m (2h 05m)
1 Stop BOG · Bogota 2h 05m
Avianca (AV 209)Airbus A320 Neo

Avianca (AV 241)Airbus A320 Neo
Avianca (AV 209)
- M
- T
- -
- T
- -
- S
- -

11:53 SDQ

00:05 SCL

11Hrs, 12m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 11:53 - SCL 00:05 11h 12m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 11:53

PTYPanama City Tocumen International Airport 15:32
PTYPanama City Tocumen International Airport 13:30

SCLSantiago Arturo Merino Benitez Airport 00:05
11h 12m (2h 02m)
1 Stop PTY · Panama City 2h 02m
Copa Airlines (CM 129)Boeing 737 800

Copa Airlines (CM 171)Boeing 737 800
Copa Airlines (CM 129)
- -
- -
- W
- T
- -
- S
- S

11:53 SDQ

23:47 SCL

10Hrs, 54m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 11:53 - SCL 23:47 10h 54m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 11:53

PTYPanama City Tocumen International Airport 15:14
PTYPanama City Tocumen International Airport 13:30

SCLSantiago Arturo Merino Benitez Airport 23:47
10h 54m (1h 44m)
1 Stop PTY · Panama City 1h 44m
Copa Airlines (CM 129)Boeing 737 800

Copa Airlines (CM 497)Boeing 737 800
Copa Airlines (CM 129)
- M
- T
- -
- T
- F
- -
- -

11:53 SDQ

03:24 SCL

14Hrs, 31m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 11:53 - SCL 03:24 14h 31m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 11:53

PTYPanama City Tocumen International Airport 18:51
PTYPanama City Tocumen International Airport 13:30

SCLSantiago Arturo Merino Benitez Airport 03:24
14h 31m (5h 21m)
1 Stop PTY · Panama City 5h 21m
Copa Airlines (CM 129)Boeing 737 800

Copa Airlines (CM 172)Boeing 737 Max 9 Passenger
Copa Airlines (CM 129)
- -
- -
- -
- -
- -
- -
- S

11:53 SDQ

03:24 SCL

14Hrs, 31m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 11:53 - SCL 03:24 14h 31m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 11:53

PTYPanama City Tocumen International Airport 18:51
PTYPanama City Tocumen International Airport 13:30

SCLSantiago Arturo Merino Benitez Airport 03:24
14h 31m (5h 21m)
1 Stop PTY · Panama City 5h 21m
Copa Airlines (CM 129)Boeing 737 800

Copa Airlines (CM 172)Boeing 737 800
Copa Airlines (CM 129)
- -
- -
- -
- -
- F
- S
- -

11:53 SDQ

03:38 SCL

14Hrs, 45m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 11:53 - SCL 03:38 14h 45m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 11:53

PTYPanama City Tocumen International Airport 19:05
PTYPanama City Tocumen International Airport 13:30

SCLSantiago Arturo Merino Benitez Airport 03:38
14h 45m (5h 35m)
1 Stop PTY · Panama City 5h 35m
Copa Airlines (CM 129)Boeing 737 800

Copa Airlines (CM 474)Boeing 737 800
Copa Airlines (CM 129)
- M
- T
- W
- -
- -
- -
- -

14:40 SDQ

05:54 SCL

14Hrs, 14m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 14:40 - SCL 05:54 14h 14m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 14:40

PTYPanama City Tocumen International Airport 21:31
PTYPanama City Tocumen International Airport 16:17

SCLSantiago Arturo Merino Benitez Airport 05:54
14h 14m (5h 14m)
1 Stop PTY · Panama City 5h 14m
Copa Airlines (CM 299)Boeing 737 Max 9 Passenger

Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
Copa Airlines (CM 299)
- -
- -
- W
- -
- -
- -
- -

14:40 SDQ

05:54 SCL

14Hrs, 14m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 14:40 - SCL 05:54 14h 14m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 14:40

PTYPanama City Tocumen International Airport 21:31
PTYPanama City Tocumen International Airport 16:17

SCLSantiago Arturo Merino Benitez Airport 05:54
14h 14m (5h 14m)
1 Stop PTY · Panama City 5h 14m
Copa Airlines (CM 299)Boeing 737 800

Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
Copa Airlines (CM 299)
- M
- T
- -
- T
- -
- -
- -

14:40 SDQ

03:47 SCL

12Hrs, 07m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:47 12h 07m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 14:40

PTYPanama City Tocumen International Airport 19:14
PTYPanama City Tocumen International Airport 16:17

SCLSantiago Arturo Merino Benitez Airport 03:47
12h 07m (2h 57m)
1 Stop PTY · Panama City 2h 57m
Copa Airlines (CM 299)Boeing 737 800

Copa Airlines (CM 474)Boeing 737 800
Copa Airlines (CM 299)
- -
- -
- -
- -
- -
- -
- S

14:40 SDQ

03:38 SCL

11Hrs, 58m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:38 11h 58m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 14:40

PTYPanama City Tocumen International Airport 19:05
PTYPanama City Tocumen International Airport 16:17

SCLSantiago Arturo Merino Benitez Airport 03:38
11h 58m (2h 48m)
1 Stop PTY · Panama City 2h 48m
Copa Airlines (CM 299)Boeing 737 Max 9 Passenger

Copa Airlines (CM 474)Boeing 737 800
Copa Airlines (CM 299)
- -
- -
- W
- -
- -
- -
- -

14:40 SDQ

03:38 SCL

11Hrs, 58m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:38 11h 58m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 14:40

PTYPanama City Tocumen International Airport 19:05
PTYPanama City Tocumen International Airport 16:17

SCLSantiago Arturo Merino Benitez Airport 03:38
11h 58m (2h 48m)
1 Stop PTY · Panama City 2h 48m
Copa Airlines (CM 299)Boeing 737 800

Copa Airlines (CM 474)Boeing 737 800
Copa Airlines (CM 299)
- M
- T
- -
- T
- F
- S
- -

14:40 SDQ

03:24 SCL

11Hrs, 44m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:24 11h 44m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 14:40

PTYPanama City Tocumen International Airport 18:51
PTYPanama City Tocumen International Airport 16:17

SCLSantiago Arturo Merino Benitez Airport 03:24
11h 44m (2h 34m)
1 Stop PTY · Panama City 2h 34m
Copa Airlines (CM 299)Boeing 737 800

Copa Airlines (CM 172)Boeing 737 Max 9 Passenger
Copa Airlines (CM 299)
- -
- -
- -
- -
- -
- -
- S

14:40 SDQ

03:24 SCL

11Hrs, 44m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:24 11h 44m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 14:40

PTYPanama City Tocumen International Airport 18:51
PTYPanama City Tocumen International Airport 16:17

SCLSantiago Arturo Merino Benitez Airport 03:24
11h 44m (2h 34m)
1 Stop PTY · Panama City 2h 34m
Copa Airlines (CM 299)Boeing 737 800

Copa Airlines (CM 172)Boeing 737 800
Copa Airlines (CM 299)
- -
- -
- -
- -
- F
- S
- -

17:08 SDQ

09:00 SCL

14Hrs, 52m 1 Stop (MIA)
SDQSanto Domingo Las Americas Airport 17:08 - SCL 09:00 14h 52m 1 Stop (MIA) Miami
SDQSanto Domingo Las Americas Airport 17:08

MIAMiami International Airport 22:45
MIAMiami International Airport 18:38

SCLSantiago Arturo Merino Benitez Airport 09:00
14h 52m (4h 07m)
1 Stop MIA · Miami 4h 07m
American Airlines (AA 1154)Boeing 737 800

American Airlines (AA 957)Boeing 777 200
American Airlines (AA 1154)
- M
- T
- W
- -
- F
- S
- S

18:15 SDQ

05:25 SCL

10Hrs, 10m 1 Stop (BOG)
SDQSanto Domingo Las Americas Airport 18:15 - SCL 05:25 10h 10m 1 Stop (BOG) Bogota
SDQSanto Domingo Las Americas Airport 18:15

BOGBogota Airport 21:30
BOGBogota Airport 19:50

SCLSantiago Arturo Merino Benitez Airport 05:25
10h 10m (1h 40m)
1 Stop BOG · Bogota 1h 40m
Avianca (AV 251)Airbus

Avianca (AV 97)Airbus A320 Neo
Avianca (AV 251)
- -
- T
- -
- T
- -
- S
- -

18:15 SDQ

05:10 SCL

9Hrs, 55m 1 Stop (BOG)
SDQSanto Domingo Las Americas Airport 18:15 - SCL 05:10 9h 55m 1 Stop (BOG) Bogota
SDQSanto Domingo Las Americas Airport 18:15

BOGBogota Airport 21:30
BOGBogota Airport 19:50

SCLSantiago Arturo Merino Benitez Airport 05:10
9h 55m (1h 40m)
1 Stop BOG · Bogota 1h 40m
Avianca (AV 251)Airbus

Avianca (AV 97)Boeing 787 8
Avianca (AV 251)
- -
- -
- W
- -
- F
- -
- S

18:25 SDQ

09:00 SCL

13Hrs, 35m 1 Stop (MIA)
SDQSanto Domingo Las Americas Airport 18:25 - SCL 09:00 13h 35m 1 Stop (MIA) Miami
SDQSanto Domingo Las Americas Airport 18:25

MIAMiami International Airport 22:45
MIAMiami International Airport 19:55

SCLSantiago Arturo Merino Benitez Airport 09:00
13h 35m (2h 50m)
1 Stop MIA · Miami 2h 50m
American Airlines (AA 2171)Boeing 737 800

American Airlines (AA 957)Boeing 777 200
American Airlines (AA 2171)
- M
- T
- W
- -
- F
- S
- S

18:38 SDQ

05:54 SCL

10Hrs, 16m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 18:38 - SCL 05:54 10h 16m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 18:38

PTYPanama City Tocumen International Airport 21:31
PTYPanama City Tocumen International Airport 20:15

SCLSantiago Arturo Merino Benitez Airport 05:54
10h 16m (1h 16m)
1 Stop PTY · Panama City 1h 16m
Copa Airlines (CM 464)Boeing 737 700

Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
Copa Airlines (CM 464)
- M
- -
- -
- -
- -
- -
- -

18:38 SDQ

05:54 SCL

10Hrs, 16m 1 Stop (PTY)
SDQSanto Domingo Las Americas Airport 18:38 - SCL 05:54 10h 16m 1 Stop (PTY) Panama City
SDQSanto Domingo Las Americas Airport 18:38

PTYPanama City Tocumen International Airport 21:31
PTYPanama City Tocumen International Airport 20:15

SCLSantiago Arturo Merino Benitez Airport 05:54
10h 16m (1h 16m)
1 Stop PTY · Panama City 1h 16m
Copa Airlines (CM 464)Boeing 737 800

Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
Copa Airlines (CM 464)
- -
- T
- W
- T
- F
- S
- -

Sorry, there are no schedules matching your filters. Try removing one. reset

What’s the most popular airline flying from Santo Domingo to Santiago?

The most popular airline flying from Santo Domingo to Santiago is Copa Airlines. Find the latest flight deals on Wego.

How far is Santiago from Santo Domingo?

The flight distance between Santo Domingo and Santiago is 5775km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 06:16. The last flight of the day departs at 06:16. See the full list of flight times on Wego.

Popular Airlines flying from Santo Domingo to Santiago

Copa Airlines ‏()

Arajet ‏()

Popular Destinations from Santiago

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Popular Hotels in Santiago

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